Product Catalog / Melanocortins

Melanotan 1

Melanotan I, also known as Afamelanotide, originally developed at the University of Arizona and now by Clinuvel Pharmaceuticals, is a synthetic peptide and analogue of the naturally occurring melanocortin peptide hormone α-melanocyte stimulating hormone (α-MSH) that has been shown to induce the production of darkening dermal pigmentation through melanogenesis and thereby subsequently reduce sun (UV) damage to UV light-exposed skin in preliminary research and human clinical trials. α-MSH activates certain melanocortin receptors in the process of exerting its effects.

AA Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.874 g/mol
PubChem SID: 16154396
Synonyms: MSH, 4-norleucyl-7-phenylalanine-alpha-; (Nle(4),D-Phe(7))alpha-MSH; MT-1 (NleFMSH)

Melanotan 2

Melanotan II is a synthetic analogue of the naturally occurring melanocortin peptide hormone α-melanocyte-stimulating hormone (α-MSH) that in usage has been shown to produce melanogenesis (part of the tanning process that produces darkening pigmentation in the skin) and have aphrodisiac effects in preliminary studies and clinical trials. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

IUPAC Name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.198 g/mol
PubChem SID: 92432
Synonyms: Melanotan-II

All rights reserved  ©  2015-2016 Eurolabs Peptides