Product Catalog / Sexual Stimulants

Gonadorelin (GnRH)

Gonadotropin-releasing hormone (GnRH), also known as follicle-stimulating hormone–releasing hormone (FSH-RH), luteinizing hormone–releasing hormone (LHRH), gonadoliberin, and by various other names in its endogenous form and as gonadorelin (INN) in its pharmaceutical form, is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.

AA Sequence: pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Molecular Formula: C57H79N17O15
Molecular Weight: 1242.363 g/mol
Synonyms: GnRH; Gonadotropin-Releasing Hormone; LHRH; Luliberin; Luteinizing Hormone-Releasing Factor; Cystorelin; Dirigestran; Factrel; FSH-Releasing Hormone; Gonadoliberin; Gonadorelin Acetate; Kryptocur; LFRH; LH-FSH Releasing Hormone; LH-Releasing Hormone; LHFSHRH; Luteinizing Hormone-Releasing Hormone

HCG Gonadotropin

Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation. hCG is a glycoprotein composed of 237 amino acids with a molecular mass of 25.7 kDa. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages. In the world of performance-enhancing drugs, HCG is increasingly used in combination with various anabolic androgenic steroid (AAS) cycles. High levels of AASs, that mimic the body's natural testosterone, trigger the hypothalamus to shut down its production of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Without GnRH, the pituitary gland stops releasing luteinizing hormone (LH). LH normally travels from the pituitary via the blood stream to the testes, where it triggers the production and release of testosterone. Without LH, the testes shut down their production of testosterone. In males, HCG helps restore and maintain testosterone production in the testes by mimicking LH and triggering the production and release of testosterone. If HCG is used for too long and in too high a dose, the resulting rise in natural testosterone would eventually inhibit its own production via negative feedback on the hypothalamus and pituitary gland.

Molecular Formula: C1105H1770N318O336S26
Molecular Weight: 25.7 kDa
Synonyms: Human chorionic gonadotropin

Melanotan 2

Melanotan II is a synthetic analogue of the naturally occurring melanocortin peptide hormone α-melanocyte-stimulating hormone (α-MSH) that in usage has been shown to produce melanogenesis (part of the tanning process that produces darkening pigmentation in the skin) and have aphrodisiac effects in preliminary studies and clinical trials. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

IUPAC Name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.198 g/mol
PubChem SID: 92432
Synonyms: Melanotan-II

PT-141 (Bremelanotide)

Bremelanotide formerly known as PT-141, is a peptide drug which has been under development by Palatin Technologies as a treatment for female sexual dysfunction (FSD), hemorrhagic shock, and reperfusion injury.

IUPAC Name: (3R,6S,9S,12S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxylic acid
Molecular Formula: C50H68N14O10
Molecular Weight: 1025.182 g/mol
PubChem SID: 6451163
Synonyms: AC1O52UR; Bremelanotide acetate; AN-30462

Triptorelin (GnRH)

Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH).

AA Sequence: H-Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Molecular Formula: C64H82N18O13
Molecular Weight: 1311.473 g/mol
PubChem SID: 25074470
Synonyms: GnRH; 6-D-Tryptophan-Luteinizing Hormone-Releasing Factor; D-Trp-6-LH-RH; Decapeptyl Depot; Triptorelin Embonate; GnRH, Trp(6)-; LHRH, Tryptophyl(6)-; Trimestral, Decapeptyl; Wy42462

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