Specification
| Name | Pinealon (EDR tripeptide) |
| Sequence | Glu-Asp-Arg (EDR) |
| Molecular weight | ≈418 Da |
| Form | Lyophilized powder |
| Strength per vial | 10 mg |
| Box contents | 10 vials, 100 mg total |
| Purity | ≥99 % (HPLC) |
Mechanism and research context
Pinealon is a short synthetic tripeptide with the sequence Glu-Asp-Arg. In neurobiological peptide research, EDR is studied in central nervous system cell systems because the sequence connects to glutamate-rich and arginine-rich signaling contexts. Cellular models of oxidative stress, including work by Kozina and colleagues on EDR in defined stress assays, provide a reference frame for laboratory comparisons. The tripeptide therefore addresses questions on neurons, glia, and redox status under controlled conditions. The molecule suits work as a compact ligand, separating peptide-mediated processes in vitro from longer scaffold peptides and running concentration-response relations with a low mass per vial. Laboratories that buy Pinealon find the EDR tripeptide at 10 mg per vial.
Reconstitution and handling
The lyophilizate is reconstituted in the laboratory with a suitable sterile solvent. The solvent is added slowly along the vessel wall and the preparation is mixed gently until the powder has fully dissolved. Because the peptide is short, small working volumes and tight dilution steps stay practical. The solution is transferred into assays promptly and kept away from direct light. Final concentration and aliquoting follow the laboratory protocol.
In vitro CNS research
In neuronal and glial culture models, Pinealon serves as a reference peptide for studies of cell stress, redox homeostasis, and survival-related signaling pathways. Oxidative stress assays use EDR to compare cellular responses to defined loads. Neurobiological series use the tripeptide to read gene-expression and signal-transduction endpoints against controls. The 10 mg vials support parallel replicates and repeated measurements in multiwell formats. Related tetrapeptide lines in the catalog, including Epithalon, extend comparative designs in gerontology peptide research.
Quality and analytics
Each Pinealon batch is checked for purity by HPLC, and the content is ≥99 %. An identity check confirms the Glu-Asp-Arg sequence. Results are documented per batch and give a reliable basis for reproducible in vitro series in neurobiological and stress-related assays.