Semax

Specification

Mechanism of action

Semax is a synthetic heptapeptide and an analogue of the ACTH(4-7) fragment. In the scientific literature it is described in neurobiological cell culture and receptor binding models. These investigations focus on signalling pathways in the central nervous system at the cellular level, including the regulation of neurotrophic factors. As a defined reference substance, Semax supports the comparison of binding behaviour and signal transduction across different cell models. Researchers who buy Semax use this 10-vial kit as a defined reference for in-vitro work.

Reconstitution and handling

The lyophilisate is reconstituted in the laboratory with a suitable sterile solvent. The resulting solution is processed promptly to preserve the defined state of the sample. Direct light exposure is avoided, and clean laboratory equipment is used throughout. For the subdivision into aliquots, a documented procedure is recommended so that volume, timing and concentration of each aliquot remain traceable. Working solutions are prepared immediately before the experiment.

In-vitro research

Semax serves as a reference substance in in vitro research. Receptor binding studies and neurobiological cell models form the main areas of use, examining how the peptide interacts with cellular targets. Further applications include the characterisation of signalling pathways, comparison series with structurally related peptides, and method development for cell based assays. All work is carried out under controlled cell culture conditions.

Quality and analytics

Every batch is tested for purity by high performance liquid chromatography (HPLC), with a specified value of ≥99 %. An identity test additionally confirms the heptapeptide sequence Met-Glu-His-Phe-Pro-Gly-Pro. The lyophilisates are assembled as a box of ten vials of identical strength. Analytical parameters such as purity, identity and molecular weight are documented per batch, so that each experimental series can rely on a uniformly characterised starting material. The documentation covers the batch identifier together with the results of the tests performed.

Available amounts per vial: 5 mg, 10 mg, 30 mg. Box of 10 vials.