Specification
| Molecule | Tirzepatide (LY3298176, dual agonist) |
| Sequence | Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys(palmitoyl-gamma-Glu-AEEA-AEEA)-Ile-Ala-Gln-Ala-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Form | Lyophilized powder |
| Strength per vial | 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 80 mg, 90 mg, 100 mg |
| Box contents | 10 vials of identical strength |
| Purity | ≥99 % (HPLC) |
Mechanism of action
Tirzepatide is a dual agonist at the GIP and GLP-1 receptors. Both incretin pathways influence glucose handling and energy balance, and in vitro models are used to study receptor binding, signal transduction and the downstream metabolic routes. As a reference ligand, the compound allows direct comparison of the activation of both receptor classes in controlled assay systems, with all findings interpreted strictly within the respective experimental design. Researchers who buy Tirzepatide use this 10-vial kit as a defined reference for in-vitro work.
Reconstitution and handling
The lyophilized powder is reconstituted in the laboratory with a suitable sterile solvent. The resulting solution is processed promptly and protected from direct light. Standard laboratory practice applies when handling the powder and the solution: a clean work surface, suitable protective equipment and a documented procedure. Volume or concentration figures are not part of this specification; the choice of solvent and preparation scheme follows the protocol of the receiving institution.
In-vitro research
Tirzepatide is used as a reference ligand in in vitro assays, including GIP/GLP-1 receptor and incretin signalling studies. Typical readouts cover binding kinetics, cAMP accumulation and downstream signalling in cell-based models. The compound supports the methodological comparison of dual versus selective receptor activation and helps characterise assay systems. All work is performed in vitro by qualified laboratories within their own research programmes.
Quality and analytics
Every lot is analysed by HPLC for purity and meets ≥99 %. The identity of the lipidated peptide sequence is confirmed as well. The measured values are documented per lot, and release follows review against the defined specification. These checks apply uniformly to all offered strengths and refer to the lyophilized powder before reconstitution.
Available amounts per vial: 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 80 mg, 90 mg, 100 mg. Box of 10 vials.