Specification
| Molecule | Tesamorelin (TH9507) |
| Sequence | [Trans-3-hexenoyl]-GHRH(1-44)-NH2 |
| CAS | 218949-48-5 |
| Molecular weight | 5.196 kDa |
| Form | Lyophilized powder |
| Strength per vial | 5 mg, 10 mg, 20 mg |
| Box contents | 10 vials of identical strength |
| Purity | ≥99 % (HPLC) |
Mechanism of action
Tesamorelin is a GHRH analog whose sequence is modified by a hexenoyl group. In research it binds GHRH receptors and is studied in endocrine cell models for signal transduction and the GH axis. The modified sequence increases stability relative to the natural GHRH fragment. Typical questions address receptor affinity, downstream signalling and the regulation of the GH axis at the cellular level. As a reference compound, tesamorelin allows different experimental approaches to be compared within a defined assay system. Researchers who buy Tesamorelin use this 10-vial kit as a defined reference for in-vitro work.
Reconstitution and handling
The lyophilized powder is reconstituted in the laboratory with a suitable sterile solvent. The solvent is added slowly along the vial wall and the preparation is mixed gently until the powder has dissolved completely. The resulting solution is processed promptly and protected from direct light until use. Volume or concentration figures are not part of this description; those parameters are set by the receiving laboratory's own protocol.
In-vitro research
In in-vitro research, tesamorelin serves as reference material for binding studies at the GHRH receptor. Endocrine cell models use the peptide to investigate signal transduction along the GH axis and the downstream cellular responses. Comparative assays that set the GHRH analog against the natural fragment also benefit from the increased stability of the modified sequence. The favourable solubility of the lyophilized powder simplifies the preparation of defined dilution series for concentration-response curves.
Quality and analytics
Every lot of tesamorelin is tested for purity by HPLC; the content is ≥99 %. An identity check additionally confirms the modified GHRH sequence of the molecule. Results are documented per lot and apply uniformly to both available strengths. This analytical characterisation provides a reliable basis for comparing data series and for the reproducibility of in-vitro experiments.
Available amounts per vial: 5 mg, 10 mg, 20 mg. Box of 10 vials.