Specification
| Molecule | Thymosin Alpha-1 (TA1, Thymalfasin) |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| CAS | 62304-98-7 |
| Molecular weight | 3.108 kDa |
| Form | Lyophilized powder |
| Strength per vial | 10 mg |
| Box contents | 10 vials of identical strength |
| Purity | ≥99 % (HPLC) |
Mechanism of action
Thymosin Alpha 1 is a synthetic 28-amino-acid peptide from thymus research. The literature describes it in immunological cell culture models; T cell mediated signalling pathways and immune cell responses are studied in vitro. As a defined reference peptide it supports comparable experimental series in which activation, proliferation and signalling parameters of immune cells are recorded and compared against positive controls. Researchers who buy Thymosin Alpha 1 use this 10-vial kit as a defined reference for in-vitro work.
Reconstitution and handling
The lyophilized powder is reconstituted in the laboratory immediately before use with a suitable sterile solvent. The resulting solution is processed promptly and protected from direct light during handling. Volume and concentration are set by the experimental design of the performing facility; this data sheet makes no specifications in that regard. A clean working environment, calibrated pipettes and use within a single experimental series support the reproducibility of the results.
In-vitro research
Thymosin Alpha 1 is used in in-vitro research as a reference for immunological questions. Positive findings are described from immunological cell culture models for T cell research as well as from activation and proliferation assays. The defined purity and the lot-related testing make the thymic peptide a reproducible point of reference for comparison series and positive controls in controlled experimental settings.
Quality and analytics
Each lot is tested for purity by HPLC and reaches at least ≥99 %. An additional identity test confirms the sequence of the 28 amino acids. Testing is performed per lot and applies uniformly to all vials in a box; the results are recorded for the respective lot. Deviations from the defined specification values would be documented and reviewed before a lot is released, and release follows only after the review is complete.