EL-03· Research peptide
Batch analytics · >99 % purity
Illustrative image; appearance and packaging may vary. 10 unlabelled vials, labelled only on the kit packaging. The selected strength applies.
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Research Use Only (RUO)
Tier I · Synthesis QC
Tier I · Synthesis QC
In-house · per step
RP-HPLC, MS confirmation, sequence verification in cleanroom.
Tier II · In-process
Tier II · In-process
Batch · final
Identity, purity, and assay before release.
Tier III · Third-party lab
Tier III · Third-party lab
External · independent
HPLC, ICP-MS, and microbiology by accredited lab.
953
satisfied
99.41%
Avg. purity 2026
4.8 ★
Store rating
EL-03 · Reference data
Tetrapeptid · Khavinson-Reihe
Aliases: Epitalon · AEDG
| Designation | Epithalon (Epitalon, AEDG) |
| Sequence | Ala-Glu-Asp-Gly (tetrapeptide) |
| Molecular weight | ≈390 Da |
| Form | Lyophilized powder |
| Strength per vial | 10 mg, 50 mg |
| Box contents | 10 vials of identical strength (100 mg total) |
| Purity | ≥99 % (HPLC) |
Epithalon is a synthetic tetrapeptide studied in research mainly in connection with telomere biology and cellular aging. Telomeres protect chromosome ends, and their shortening across successive cell divisions correlates in models with replicative senescence. Telomerase, including through the subunit hTERT, can lengthen telomeric DNA. In cell and tissue models, Epithalon is used to characterise the relationship between peptide signals, telomerase activity and the stability of telomere length. Laboratories that buy Epithalon receive the tetrapeptide at 10 mg per vial.
The lyophilizate is reconstituted in the laboratory with a suitable sterile solvent. The solvent is added slowly along the vessel wall and the preparation is mixed gently until the powder has dissolved completely. Because of the short sequence, Epithalon usually dissolves quickly. The resulting solution is processed promptly, since peptides in solution respond more readily to environmental influences. Until use, the reagent is protected from direct light. Concentration and volume are set by the laboratory in its own protocol.
In in vitro research, Epithalon serves as a defined reference peptide for aging and longevity studies in cell lines. Typical endpoints are telomerase activity, hTERT expression, telomere length by qPCR or TRF analysis, and senescence markers such as p16 or SA-β-Gal. Fibroblast and epithelial cell cultures are often used to compare replication limits and stress-induced aging pathways. Epithalon can be prepared in defined dilution series to test dose-dependent effects on telomere and cell-cycle parameters in controlled assays.
Each batch of Epithalon is tested for purity by HPLC, and the content is ≥99 %. An identity check confirms the tetrapeptide sequence Ala-Glu-Asp-Gly. Results are documented per batch. This analytical characterisation supports reproducible in vitro experiments when telomere and senescence parameters are compared across measurement series.
Available amounts per vial: 10 mg, 50 mg. Box of 10 vials.
Every batch is analyzed by an independent laboratory via HPLC before shipment. We document purity (avg. 99.41% in 2026), mass spectrometry identity, and sterility. Production follows GMP standards in ISO-certified laboratories.
For research use only. Not for human or animal use, diagnosis, therapy or consumption.
A box contains exactly 10 identical, unlabelled vials of the selected variant. The product label is on the outer box.
Available amounts per vial: 10 mg, 50 mg.
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