EL-13· Research peptide
SS-31
Batch analytics · >99 % purity
Research Use Only (RUO)
Illustrative image; appearance and packaging may vary. 10 unlabelled vials, labelled only on the kit packaging. The selected strength applies.
- T.01Avg. 99.41% HPLC (2026)Every batch independently analyzed
- T.0214-day money backOn purity deviation
- T.03GMP-compliant productionISO-certified lab partners
- T.04Discreet orderingNeutral packaging
Three independent verification layers
- Q.01
Tier I · Synthesis QC
Tier I · Synthesis QC
In-house · per step
RP-HPLC, MS confirmation, sequence verification in cleanroom.
- Q.02
Tier II · In-process
Tier II · In-process
Batch · final
Identity, purity, and assay before release.
- Q.03
Tier III · Third-party lab
Tier III · Third-party lab
External · independent
HPLC, ICP-MS, and microbiology by accredited lab.
953
satisfied
99.41%
Avg. purity 2026
4.8 ★
Store rating
EL-13 · Reference data
Mitochondrien-zielendes Tetrapeptid
- Sequence
- D-Arg-Dmt-Lys-Phe-NH₂
- Molecular weight
- 639.79 Da
- CAS
- 736992-21-5
- Origin
- Synthese · Zürich (CH)
- Application fields
- A.04
Aliases: Elamipretide · Bendavia
About SS-31 (SS-31)
Specification
| Name | SS-31 (elamipretide, MTP-131) |
| Sequence | Synthetic tetrapeptide (Szeto-Schiller class) |
| Molecular weight | ≈639 Da |
| Form | Lyophilized powder |
| Strength per vial | 10 mg, 50 mg |
| Box contents | 10 vials of the same strength (100 mg total) |
| Purity | ≥99 % (HPLC) |
Mechanism of action
SS-31, known internationally as elamipretide, belongs to the mitochondria-targeting peptides. The molecule interacts with cardiolipin, a phospholipid of the inner mitochondrial membrane. Cardiolipin arranges the proteins of the respiratory chain and shapes the curvature of the cristae. In cell and tissue models, work follows how SS-31 stabilizes membrane tension, eases load on the electron transport chain, and lowers formation of reactive oxygen species under stress. The focus is mitochondrial bioenergetics: ATP synthesis, membrane potential, and organelle integrity. Laboratories that buy SS-31 take elamipretide at 10 mg per vial.
Reconstitution and handling
The lyophilizate is reconstituted in the laboratory with a suitable sterile solvent. The solvent is added slowly along the vessel wall and the preparation is mixed gently until the powder has fully dissolved. The resulting solution is used promptly in the planned assays, because peptides in solution respond more readily to surrounding conditions. Until use, the reagent is kept out of direct light. The laboratory running the work sets concentration and volume in its own protocol.
In-vitro research
In in-vitro research, SS-31 is a reference substance for mitochondrial function assays. Typical uses include measurements of mitochondrial membrane potential, OCR and ECAR profiles in isolated mitochondria or intact cells, and ROS detection with fluorescent probes. Models with induced oxidative load or a disrupted respiratory chain use the peptide to follow recovery of membrane integrity and ATP production. Interaction studies with cardiolipin-containing liposomes or reconstituted membrane systems characterize binding affinity and the effect on membrane fluidity. The compact tetrapeptide structure makes defined dilution series straightforward for concentration-response curves in multiwell plates.
Quality and analytics
Each batch of SS-31 is checked by HPLC for purity; the content is ≥99 %. An identity check confirms the tetrapeptide backbone of elamipretide. Results are recorded per batch. This analytical profile gives a reliable basis for comparing measurement series and for the reproducibility of mitochondrial in-vitro experiments.
Available amounts per vial: 10 mg, 50 mg. Box of 10 vials.
Quality, purity & batch documentation
Every batch is analyzed by an independent laboratory via HPLC before shipment. We document purity (avg. 99.41% in 2026), mass spectrometry identity, and sterility. Production follows GMP standards in ISO-certified laboratories.
Frequently asked questions
For research use only. Not for human or animal use, diagnosis, therapy or consumption.
A box contains exactly 10 identical, unlabelled vials of the selected variant. The product label is on the outer box.
Available amounts per vial: 10 mg, 50 mg.
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