MOTS-c

Specification

Mechanism of action

MOTS-c is a mitochondrial-derived peptide of sixteen amino acids. In cell biology publications it is described in connection with energy metabolism and metabolic signal transduction. In vitro work examines cellular stress responses and metabolic pathways that can be recorded systematically in cell culture models. The defined sequence MRWQEMGYIFYPRKLR makes the peptide a reproducible reference point for comparable experimental series, positive controls and the calibration of metabolic readouts. Researchers who buy MOTS-c use this 10-vial kit as a defined reference for in-vitro work.

Reconstitution and handling

The lyophilized powder is reconstituted in the laboratory with a suitable sterile solvent immediately before use. The resulting solution is processed promptly and protected from direct light during handling. Volume and concentration are set by the experimental plan of the receiving laboratory; this data sheet makes no recommendations in that regard. A clean workspace, calibrated pipettes and use within a single experimental series support the reproducibility of results. For consistency between reconstitution, dilution and measurement, each step is recorded in the experimental protocol so that runs remain comparable.

In-vitro research

For MOTS-c, positive findings from cell biology models on energy metabolism and mitochondrial signal transduction are described in in vitro research. The focus is on cell culture approaches that record metabolic parameters, stress responses and signal transduction pathways under controlled conditions. Its lyophilized form and batch-wise testing make the peptide a reproducible starting material for comparison series and positive controls. As a mitochondrial-derived peptide, MOTS-c is of interest for in vitro questions at the interface of mitochondrial and cellular signalling.

Quality and analytics

Every batch is tested for purity by HPLC and reaches at least ≥99 %. An additional identity test confirms the sequence of the sixteen amino acids. Testing is performed batch by batch and applies uniformly to all vials in a box; results are recorded for the respective batch. Deviations from the specified values would be documented and reviewed before a batch is released.

Available amounts per vial: 10 mg, 20 mg, 40 mg. Box of 10 vials.