TB-500

Specification

Mechanism of action

TB-500 is a fragment of Thymosin Beta-4 and binds to actin, the central structural protein of the cytoskeleton. The literature describes the peptide in cell migration, cytoskeletal and regeneration models. Research focuses on cell movement, tissue remodeling and differentiation in vitro. As a reagent with a defined sequence and purity, TB-500 makes these processes comparable in controlled experimental setups and serves as a benchmark for binding and migration assays. Researchers who buy TB-500 use this 10-vial kit as a defined reference for in-vitro work.

Reconstitution and handling

The lyophilizate is provided as a powder and is reconstituted with a suitable sterile solvent in the laboratory immediately before use. The resulting solution is processed promptly, since the peptide is more sensitive in dissolved form than as a lyophilizate. During handling the solution is protected from direct light. Volume or concentration figures are not part of this data sheet; their definition is left to the performing facility. A clean working environment and consumption within the respective experimental series support the reproducibility of results.

In-vitro research

TB-500 serves as a reference reagent for in vitro research on cell migration and cytoskeletal models. Typical applications include migration assays in cell culture, studies of actin dynamics and investigations of tissue remodeling and differentiation in defined model systems. Lot-specific testing of purity and sequence makes the reagent a reproducible benchmark for comparison series and positive controls. The selection of models and documentation of the experimental series remain with the performing laboratory.

Quality and analytics

Every lot is tested by HPLC for purity and meets at least ≥99 %. An additional identity check confirms the peptide sequence and thus its correspondence to the actin-binding Thymosin Beta-4 fragment. Testing is performed per lot and applies uniformly to all vials in a box; results are recorded for each individual lot. In its lyophilized form the material remains stable as a powder until reconstitution and allows a consistent fill across the ten vials of the box.

Available amounts per vial: 5 mg, 10 mg. Box of 10 vials.